Twenty years after the great drought of 2020, citizens in California and across the United States live under the government's watchful eye. In this age of intrusion, competition for resources and jobs is fierce. One mistake can be disastrous.
Maggie, Jasmine, Sydney, and Lena are strangers with one thing in common: they each have nothing left to live for. All these women need is a fresh start, but they'll find the cost is more than they could ever have imagined. A secretive biogenetics company offers them a mysterious serum that promises to change their identities, giving them great fortune and power. Is such a serum too good to be true?
The women find that their new success draws them into a world of rivalry and blackmail, and by the time they discover the truth about the serum, it's too late. The evil scientist who created it only cares about money, regardless of how many people get hurt.
After reuniting for follow-up testing, the four women realize their only choice is banding together to stop testing of the serum. They're watched from every side, but they must try to salvage what little is left of the humanity of Earth.